Hyperfixation of HMPAO in subacute ischemic stroke leading to spuriously high estimates of cerebral blood flow by SPECT.

نویسندگان

  • B Sperling
  • N A Lassen
چکیده

s of Literature .......................... 331 Major Ongoing Stroke Trials .......................... 342 News from the American Heart Association .A345 AHA Meetings Calendar. A346 by gest on N ovem er 7, 2016 http://strhajournals.org/ D ow nladed from

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Spuriously High Estimates of Cerebral Blood Flow by SPECT

W e want to report an error in interpreting d,l-hexamethylpropylene amine oxime (HMPAO) tomograms as cerebral blood flow (CBF) in subacute ischemic stroke cases. By simultaneously studying CBF by `33Xe dynamic single-photon emission computed tomography (SPECT), an obvious discrepancy was noted in that the HMPAO tomograms grossly exaggerated the reflow hyperemia following spontaneous reperfusion...

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Spurious hyperfixation of hexamethylpropyleneamine oxime in acute embolic stroke.

A 71-year-old man with atrial fibrillation suddenly had an embolism in the right middle cerebral artery. Single-photon emission CT was performed 4 hours after the onset of stroke and revealed markedly elevated 99mTc-hexamethylpropyleneamine oxime (HMPAO) uptake in the right frontotemporoparietal region. This area of HMPAO hyperfixation corresponded to the area of infarction, as determined by CT...

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Spontaneous reperfusion after ischemic stroke is associated with improved outcome.

BACKGROUND AND PURPOSE The rationale behind thrombolytic therapy in acute ischemic stroke is penumbral salvage by rapid restoration of cerebral blood flow. The relationship, however, between early reperfusion (potentially composed of both nutritional and nonnutritional components) and outcome remains unclear. METHODS To establish the relationship between reperfusion parameters and outcome var...

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Assessment of regional cerebral blood flow (rCBF) in ischemic stroke using Tc-99m HMPAO SPECT--comparison with CT and MR findings.

To assess the regional cerebral blood flow (rCBF) in ischemic stroke, we analyzed the findings of single photon emission computed tomography (SPECT) using technetium-99m hexamethyl propyleneamine oxime (Tc-99m HMPAO). The SPECT images revealed abnormal areas of decreased perfusion in 29 out of 31 subjects (93.5%), which represented a higher detection rate than those for CT and MR (89.5%, respec...

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Leukocyte infiltration in acute hemispheric ischemic stroke.

BACKGROUND AND PURPOSE The dynamics of leukocyte infiltration in human cerebral ischemia were studied using technetium-99m hexamethylpropyleneamine oxime (99mTc HMPAO)-labeled leukocyte brain single-photon emission computed tomography (SPECT). METHODS Twenty-two patients diagnosed as having hemispheric ischemic stroke were examined with 99mTc HMPAO brain SPECT for cerebral blood flow study an...

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عنوان ژورنال:
  • Stroke

دوره 24 2  شماره 

صفحات  -

تاریخ انتشار 1993